XCOPRI can be prescribed as monotherapy or adjunctive therapy1
WEEK 11 &
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Maximum dosage: Dosage may be increased above 200 mg/day by increments of 50 mg/day every 2 weeks to a maximum of 400 mg/day.
Patients with mild or moderate hepatic impairment: 200 mg/day is the maximum dosage. XCOPRI is not recommended for use in patients with severe hepatic impairment.
See Prescribing Information for additional Dosage and Administration instructions.
Below is an example* of a titration schedule for prescribing XCOPRI. After you have titrated up to find the right maintenance dosage, maintenance blister packs and bottles are available.
XCOPRI Titration Blister Packs
Designed to simplify the titration schedule of XCOPRI. At-a-glance instructions have been included to assist you and your patients as XCOPRI dosages are increased over time.1
12.5 mg / 25 mg (28-day supply)
50 mg / 100 mg (28-day supply)
150 mg / 200 mg (28-day supply)
XCOPRI Maintenance Blister Packs and Bottles
Designed to give you the flexibility to find the dosage that is right for your individual patients.1
• 250 mg [28-day supply]
• 350 mg [28-day supply]
Maintenance bottles available:
• 50 mg (30-count bottle)
• 100 mg (30-count bottle)
• 150 mg (30-count bottle)
• 200 mg (30-count bottle)
Managing the Adjunctive Use of XCOPRI
In this interactive video, watch as Lawrence Seiden, MD, and Barry Gidal, PharmD, discuss anti-seizure medication (ASM) dosing considerations to be aware of when adding XCOPRI to a patient’s treatment regimen. Discover essential information regarding the optimization of XCOPRI’s efficacy, plus potential ways to minimize side effects—and be sure to bookmark for reference.
XCOPRI makes the concentration of some drugs go up. Consider decreasing the dosage of clobazam, phenytoin, and phenobarbital early in XCORPI titration.1,2
If a patient experiences common adverse events, consider decreasing the dosage of other ASMs.1,2*
Find more information for prescribing XCOPRI with concomitant medications